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| Name | W | L | SV | ERA | G | GS | IP | HA | R | ER | HR | BB | K | WHIP | OAVG | BABIP | WAR |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Josh Beckett SP | 6 | 1 | 0 | 2.76 | 11 | 11 | 71.2 | 59 | 28 | 22 | 7 | 19 | 65 | 1.09 | .218 | .260 | 1.5 |
| Kevin Gregg RP | 2 | 0 | 0 | 3.00 | 9 | 0 | 18.0 | 10 | 6 | 6 | 1 | 5 | 16 | 0.83 | .164 | .196 | 0.3 |
| Kiko Calero RP | 0 | 0 | 0 | 3.00 | 3 | 0 | 3.0 | 5 | 1 | 1 | 1 | 1 | 0 | 2.00 | .357 | .308 | -0.1 |
| Dontrelle Willis SP | 9 | 8 | 0 | 3.32 | 39 | 16 | 149.0 | 146 | 59 | 55 | 9 | 52 | 124 | 1.33 | .256 | .310 | 3.0 |
| Kevin Brown SP | 11 | 5 | 0 | 3.85 | 28 | 28 | 159.0 | 172 | 74 | 68 | 10 | 53 | 124 | 1.42 | .276 | .329 | 3.2 |
| Livan Hernandez RP | 3 | 2 | 1 | 3.98 | 38 | 5 | 81.1 | 91 | 42 | 36 | 14 | 28 | 69 | 1.46 | .280 | .317 | -0.1 |
| Robb Nen RP | 5 | 5 | 6 | 4.35 | 55 | 0 | 49.2 | 56 | 26 | 24 | 6 | 16 | 52 | 1.45 | .281 | .350 | 0.8 |
| Juan López SP | 12 | 10 | 0 | 4.45 | 33 | 33 | 208.1 | 209 | 108 | 103 | 18 | 63 | 175 | 1.31 | .260 | .309 | 4.0 |
| Pedro Villegas SP | 9 | 11 | 0 | 4.55 | 32 | 32 | 198.0 | 195 | 109 | 100 | 35 | 58 | 166 | 1.28 | .252 | .277 | 1.1 |
| A J Burnett RP | 4 | 2 | 2 | 4.80 | 34 | 0 | 65.2 | 66 | 37 | 35 | 6 | 38 | 68 | 1.58 | .261 | .331 | 0.2 |
| Iván Pérez SP | 7 | 4 | 0 | 5.02 | 15 | 15 | 80.2 | 94 | 47 | 45 | 10 | 23 | 72 | 1.45 | .293 | .346 | 1.2 |
| Al Leiter RP | 3 | 2 | 1 | 5.15 | 29 | 0 | 64.2 | 85 | 41 | 37 | 6 | 22 | 57 | 1.65 | .321 | .389 | 0.6 |
| Josh Johnson SP | 7 | 11 | 0 | 6.03 | 35 | 21 | 137.1 | 164 | 98 | 92 | 26 | 64 | 133 | 1.66 | .300 | .353 | -0.2 |
| Dan Miceli RP | 2 | 0 | 0 | 6.06 | 13 | 0 | 16.1 | 20 | 11 | 11 | 4 | 4 | 14 | 1.47 | .290 | .314 | -0.2 |
| Bryan Harvey CL | 1 | 10 | 29 | 6.07 | 60 | 0 | 56.1 | 66 | 40 | 38 | 13 | 24 | 71 | 1.60 | .288 | .363 | -0.5 |
| Guillermo Mota RP | 2 | 3 | 0 | 7.02 | 29 | 0 | 33.1 | 49 | 27 | 26 | 5 | 15 | 25 | 1.92 | .343 | .383 | -0.2 |
| Ricky Nolasco RP | 1 | 2 | 0 | 8.26 | 18 | 0 | 40.1 | 62 | 37 | 37 | 17 | 7 | 41 | 1.71 | .354 | .378 | -1.3 |
| Chris Hammond RP | 0 | 0 | 0 | 8.44 | 3 | 0 | 5.1 | 12 | 5 | 5 | 1 | 1 | 1 | 2.44 | .444 | .440 | -0.1 |
| Juan Carlos Oviedo RP | 0 | 1 | 0 | 11.81 | 4 | 0 | 5.1 | 10 | 7 | 7 | 2 | 1 | 1 | 2.06 | .435 | .364 | -0.2 |
