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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | IP | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | Roger Clemens# | 270.0 | 2015 | |
| 2 | Gaylord Perry# | 253.0 | 2014 | |
| 3 | Christy Mathewson# | 250.0 | 2016 | |
| 3 | Dwight Gooden# | 250.0 | 2016 | |
| 3 | Roger Clemens# | 250.0 | 2016 | |
| 6 | Smoky Joe Wood# | 248.0 | 2016 | |
| 7 | Sandy Koufax# | 247.0 | 2014 | |
| 7 | Sandy Koufax# | 247.0 | 2015 | |
| 9 | Dutch H Leonard# | 245.0 | 2015 | |
| 9 | Walter Johnson# | 245.0 | 2015 | |
| 11 | Ed Walsh# | 244.0 | 2015 | |
| 11 | Pete Alexander# | 244.0 | 2016 | |
| 13 | Frank Tanana# | 243.0 | 2015 | |
| 14 | Frank Tanana# | 242.0 | 2016 | |
| 15 | Justin Verlander# | 241.0 | 2015 | |
| 15 | Bert Blyleven# | 241.0 | 2016 | |
| 17 | Dazzy Vance# | 240.0 | 2015 | |
| 17 | Ron Guidry# | 240.0 | 2015 | |
| 17 | Roy Halladay# | 240.0 | 2016 | |
| 20 | Ed Walsh# | 239.0 | 2016 | |
| 21 | Eddie Cicotte# | 238.0 | 2016 | |
| 21 | Greg Maddux# | 238.0 | 2014 | |
| 21 | Smoky Joe Wood# | 238.0 | 2015 | |
| 21 | J R Richard# | 238.0 | 2015 | |
| 21 | Ed Walsh# | 238.0 | 2014 | |
| 26 | Ron Guidry# | 237.0 | 2016 | |
| 26 | Christy Mathewson# | 237.0 | 2015 | |
| 26 | Sandy Koufax# | 237.0 | 2016 | |
| 26 | Tom Seaver# | 237.0 | 2016 | |
| 30 | Dwight Gooden# | 236.0 | 2015 | |
| 31 | Lefty Grove# | 235.0 | 2014 | |
| 32 | Gaylord Perry# | 234.0 | 2015 | |
| 32 | Brandon Webb# | 234.0 | 2014 | |
| 32 | J R Richard# | 234.0 | 2014 | |
| 32 | Greg Maddux# | 234.0 | 2015 | |
| 36 | Carl Hubbell# | 233.0 | 2015 | |
| 36 | Rube Waddell# | 233.0 | 2015 | |
| 36 | Ron Guidry# | 233.0 | 2014 | |
| 36 | Dazzy Vance# | 233.0 | 2014 | |
| 40 | Walter Johnson# | 232.0 | 2016 | |
| 40 | Tom Seaver# | 232.0 | 2015 | |
| 40 | Randy Jones# | 232.0 | 2016 | |
| 43 | Jim Palmer# | 231.0 | 2016 | |
| 43 | Jim Palmer# | 231.0 | 2014 | |
| 43 | Christy Mathewson# | 231.0 | 2014 | |
| 46 | Carl Hubbell# | 230.0 | 2014 | |
| 46 | Brandon Webb# | 230.0 | 2015 | |
| 46 | Brandon Webb# | 230.0 | 2016 | |
| 49 | Pete Alexander# | 229.0 | 2015 | |
| 49 | Lefty Gomez# | 229.0 | 2016 | |
| 49 | Red Faber# | 229.0 | 2016 | |
| 49 | Walter Johnson# | 229.0 | 2014 | |
| 49 | J R Richard# | 229.0 | 2016 | |
| 49 | Bret Saberhagen# | 229.0 | 2016 | |
| 55 | Bob Gibson# | 228.0 | 2016 | |
| 56 | Jose Rijo# | 227.0 | 2015 | |
| 56 | Bob Gibson# | 227.0 | 2015 | |
| 58 | Eddie Cicotte# | 226.0 | 2015 | |
| 58 | Gaylord Perry# | 226.0 | 2016 | |
| 58 | Bob Gibson# | 226.0 | 2014 | |
| 58 | Pedro J Martinez# | 226.0 | 2015 | |
| 58 | Bret Saberhagen# | 226.0 | 2014 | |
| 58 | Don Sutton# | 226.0 | 2015 | |
| 64 | Rube Waddell# | 225.0 | 2014 | |
| 64 | Eddie Cicotte# | 225.0 | 2014 | |
| 64 | Eddie Plank# | 225.0 | 2015 | |
| 64 | Justin Verlander# | 225.0 | 2014 | |
| 64 | Cy Young# | 225.0 | 2014 | |
| 69 | Mike Scott# | 224.0 | 2014 | |
| 69 | Roger Clemens# | 224.0 | 2014 | |
| 69 | Carl Hubbell# | 224.0 | 2016 | |
| 72 | Hal Newhouser# | 223.0 | 2016 | |
| 73 | Clark Griffith# | 222.0 | 2014 | |
| 73 | Pete Alexander# | 222.0 | 2014 | |
| 75 | Dazzy Vance# | 221.0 | 2016 | |
| 75 | David Price# | 221.0 | 2016 | |
| 75 | Jim Bunning# | 221.0 | 2014 | |
| 78 | Whitey Ford# | 220.0 | 2015 | |
| 78 | Red Ruffing# | 220.0 | 2015 | |
| 78 | Hal Newhouser# | 220.0 | 2015 | |
| 81 | Johan Santana# | 219.0 | 2015 | |
| 81 | Dutch E Leonard# | 219.0 | 2014 | |
| 81 | Don Sutton# | 219.0 | 2014 | |
| 81 | Randy Jones# | 219.0 | 2014 | |
| 81 | Tom Seaver# | 219.0 | 2014 | |
| 81 | Dan Haren# | 219.0 | 2015 | |
| 87 | Dwight Gooden# | 218.0 | 2014 | |
| 87 | Bert Blyleven# | 218.0 | 2015 | |
| 87 | Pedro J Martinez# | 218.0 | 2014 | |
| 90 | Hal Newhouser# | 217.0 | 2014 | |
| 90 | Cy Young# | 217.0 | 2016 | |
| 90 | Curt Schilling# | 217.0 | 2014 | |
| 90 | Roy Halladay# | 217.0 | 2015 | |
| 94 | Don Sutton# | 216.0 | 2016 | |
| 94 | Dave Stieb# | 216.0 | 2016 | |
| 94 | Teddy Higuera# | 216.0 | 2014 | |
| 97 | Dizzy Dean# | 215.0 | 2014 | |
| 97 | Kevin Appier# | 215.0 | 2016 | |
| 97 | Jake Peavy# | 215.0 | 2016 | |
| 97 | CC Sabathia# | 215.0 | 2015 |
